Sizes Available: 50 mL / 1.7 fl. oz. and 30 mL / 1 fl. oz.
Skin Concerns: Premature aging, fine lines, wrinkles, weakened skin barrier, dehydration, visible redness, environmental damage, dullness, loss of skin resilience
Skin Types: All skin types, including dry, normal, combination, oily, and sensitive skin
Texture: Lightweight, fast-absorbing antioxidant and barrier-supporting serum
Recommended Use: Morning and evening as part of a daily preventative and corrective skincare routine
ZO Skin Health Daily Power Defense is an advanced antioxidant and skin barrier repair serum designed to strengthen the skin’s natural defenses, improve hydration, and protect against environmental stressors that accelerate visible aging. As one of ZO Skin Health’s bestselling treatments, this clinically tested formula combines proprietary antioxidant technology, plant-derived polysaccharides, and specialized skin-supporting enzymes to promote a healthier, smoother, and more resilient complexion.
Healthy, youthful-looking skin begins with a strong protective barrier. Daily exposure to UV radiation, pollution, oxidative stress, and environmental aggressors can weaken the skin’s defenses, contribute to moisture loss, and accelerate the appearance of fine lines, wrinkles, dullness, and visible irritation. When barrier function becomes compromised, skin may become increasingly vulnerable to dehydration, sensitivity, and premature aging.
Daily Power Defense takes a comprehensive approach to these concerns by addressing both skin barrier integrity and the environmental factors associated with premature aging. Rather than functioning as a conventional moisturizer or basic antioxidant serum, this advanced treatment helps reinforce the skin’s protective barrier while supporting hydration, comfort, and long-term resilience.
At the heart of the formula is ZO-RRS2®, ZO Skin Health’s exclusive plant stem cell complex designed to help neutralize free radicals and soothe the appearance of visible redness. This targeted antioxidant technology helps defend against oxidative stress while promoting a calmer, more balanced-looking complexion.
The formula also features ZPOLY™, a proprietary plant-derived polysaccharide complex that provides extended hydration while helping minimize the visible signs of premature aging. By supporting moisture retention and skin comfort, ZPOLY™ helps maintain a smoother, more supple complexion throughout the day.
Vitamins A and E provide additional antioxidant support, helping defend against environmental factors that contribute to visible skin aging. Specialized enzymes, including Micrococcus Lysate and Arabidopsis Thaliana Extract, complement the formula by supporting optimal skin cell health and overall skin resilience.
Clinically tested to deliver visibly healthier-looking skin in just two weeks, Daily Power Defense is designed to become the foundation of a consistent preventative and corrective skincare routine. With continued use, skin appears stronger, calmer, more hydrated, and better equipped to maintain its youthful-looking appearance.
Suitable for all skin types, Daily Power Defense can be incorporated into both simple daily skincare routines and advanced ZO Skin Health regimens targeting wrinkles, pigmentation, texture, or other visible signs of aging.
Clinical Results & Expected Improvements
Visibly Healthier Skin in 2 Weeks
ZO Skin Health reports visibly healthier-looking skin after two weeks of consistent use.
Improved Barrier Support
Helps strengthen the skin’s protective barrier to maintain moisture and improve resilience.
Extended Hydration
ZPOLY™ technology supports prolonged hydration for skin that feels softer, smoother, and more comfortable.
Antioxidant Defense
ZO-RRS2® and Vitamins A and E help defend against oxidative stress associated with premature visible aging.
Visible Redness Support
The proprietary plant stem cell complex helps soothe the appearance of redness for a calmer-looking complexion.
The supplied manufacturer information identifies visible improvements after two weeks but does not provide specific clinical improvement percentages.
What Makes This Unique
ZO-RRS2® Antioxidant Technology
ZO-RRS2® is an exclusive plant stem cell complex developed to help neutralize free radicals while soothing visible redness.
Environmental stressors can contribute to oxidative damage, uneven skin quality, and premature visible aging. ZO-RRS2® provides targeted antioxidant support to help maintain a healthier-looking complexion.
Its soothing benefits also make it valuable for skin experiencing visible redness or environmental stress.
ZPOLY™ Hydration Technology
ZPOLY™ is a proprietary plant-derived polysaccharide complex designed to provide extended hydration while helping minimize signs of premature aging.
By supporting moisture retention and overall skin comfort, this technology helps maintain a smoother, more supple, and resilient-looking complexion.
Vitamins A + E
These antioxidant vitamins help defend against environmental factors associated with visible skin aging.
Vitamin E provides antioxidant and skin-conditioning support, while Vitamin A contributes to the formula’s comprehensive antioxidant defense.
Micrococcus Lysate + Arabidopsis Thaliana Extract
These specialized enzyme ingredients are included to encourage optimal skin cell health and support the skin’s natural protective functions.
Together, these technologies make Daily Power Defense a multifunctional treatment focused on barrier strength, antioxidant protection, hydration, and long-term skin quality.